Alpha7 nicotinic acetylcholine receptor inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 231/40 (2006.01) A61K 31/4155 (2006.01) A61P 25/00 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2729606

The present invention provides compounds and compositions, methods of making them, and methods of using them to modulate .alpha.7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Pro-vided compounds can affect, among other things, neurological, psychiatric and/or inflammatory systems.

L'invention concerne des composés et des compositions, des procédés de fabrication de ceux-ci, et des procédés d'utilisation de ceux-ci pour moduler des récepteurs nicotiniques a7 de l'acétylcholine et/ou traiter un quelconque parmi divers troubles, diverses maladies et diverses affections. Des composés fournis peuvent affecter, entre autres choses, les systèmes neurologique, psychiatrique et/ou inflammatoire.

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