Alphavirus vectors for respiratory pathogen vaccines

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/215 (2006.01) A61K 38/47 (2006.01) A61K 39/02 (2006.01) A61K 39/12 (2006.01) A61K 39/145 (2006.01) A61K 39/155 (2006.01) A61P 31/12 (2006.01) C12N 7/01 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2567446

Described herein are compositions and methods for stimulating an immune response to one or more proteins derived from one or more respiratory pathogens. In particular, the invention relates to alphavirus replicons, alphavirus vector constructs, alphavirus replicon particles expressing one or more antigens derived from one or more respiratory pathogens as well as to method of making and using these immunogenic compositions.

Compositions et procédés de stimulation d'une réponse immune à une ou plusieurs protéines dérivées d'un ou plusieurs pathogènes respiratoires. Plus particulièrement réplicon d'alphavirus, constructions de vecteurs d'alphavirus, particules de réplicon d'alphavirus exprimant un ou plusieurs antigènes dérivés d'un ou plusieurs pathogènes respiratoires et procédé de fabrication et d'utilisation de ces compositions immunogènes.

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