C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/02 (2006.01) A01N 43/04 (2006.01) A61K 31/70 (2006.01) C07H 21/04 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2400573
The present invention provides compositions and methods for controlling the behavior of a cell, tissue or organism through antisense modulation of mRNA processing, using antisense compounds which does not support cleavage of the mRNA target.
La présente invention concerne des compositions et des procédés permettant de commander le comportement d'une cellule, d'un tissu ou d'un organisme, par modulation antisens de la maturation d'ARN messager, impliquant l'utilisation de composés antisens qui n'assurent pas le clivage de la cible d'ARN messager.
Baker Brenda F.
Bennett C. Frank
Crooke Stanley T.
Freier Susan M.
Karras James G.
Borden Ladner Gervais Llp
Isis Pharmaceuticals Inc.
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