A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/505 (2006.01) A61K 31/165 (2006.01) A61K 31/415 (2006.01) A61K 31/4439 (2006.01) A61K 31/5375 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61K 45/06 (2006.01) A61P 9/12 (2006.01)
Patent
CA 2669535
Therapeutic combinations and pharmaceutical compositions are provided comprising ambrisentan and an inhibitor of renin activity or release. Such combinations and compositions are useful to treat hypertensive disorders, particularly pulmonary hypertension conditions such as pulmonary arterial hypertension, to prevent cardiovascular adverse events related thereto, to enhance pulmonary function and to extend time to clinical worsening in a subject having a pulmonary hypertension condition.
Combinaisons thérapeutiques et compositions pharmaceutiques comprenant de l'ambrisentan et un inhibiteur d'activité ou de libération de la rénine. De telles combinaisons et de telles compositions sont utilisées pour traiter les troubles de l'hypertension, en particulier les affections liées à l'hypertension pulmonaire, comme l'hypertension artérielle pulmonaire, pour éviter les événements indésirables cardiovasculaires qui lui sont associés, pour stimuler la fonction pulmonaire, et allonger le délai vers l'aggravation clinique chez un sujet souffrant d'hypertension pulmonaire.
Gilead Colorado Inc.
Mcfadden Fincham
LandOfFree
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