Ambulatory clearance function monitor

Details Ambulatory clearance function monitor Ambulatory clearance function monitor

G - Physics

01

T

G01T 1/161 (2006.01) A61B 5/00 (2006.01)

Patent

CA 2123795

2123795 9310470 PCTABS00022 Accurate and continuous monitoring of clearance function is obtained by determining the depletion of a labelled substance from the extracellular body fluid using an external monitor (10) which detects the label from within a defined tissue volume. The detector (4) of the external monitor (10) is contained within a collimator (3) which functions to both exclude external influences and to functionally isolate the volume of extracellular fluid to be monitored. Also, a method for determining and expressing a clearance function in a subject includes the steps of allowing a time sufficient to permit establishment of equilibrium of a detectable substance in the extracellular space in the subject, obtaining first and second measures, at first and second times, of the detectable substance in the extracellular fluid within a defined tissue volume in the subject, and determining the slope of the measures over the time interval.

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