Amelioration of macular degeneration and other ophthalmic...

A - Human Necessities – 61 – K

Patent

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A61K 31/445 (2006.01)

Patent

CA 2546042

Methods for the treatment or prevention of a number of ocular diseases or disorders are disclosed. In particular, methods are disclosed for the amelioration of macular degeneration, diabetic retinophaty and other retinopathies, as well as uveitis, presbyopia, dry eye, glaucoma, blepharitis and rosacea of the eye. The methods comprise administration of a compositions comprising an ophthalmologically acceptable carrier or diluent and a hydoxylamine compound in a therapeutically sufficient amount to prevent, retard the development or reduce the symptoms of one or more of the ophthalmic conditions.

La présente invention concerne des procédés pour traiter ou prévenir un certain nombre de maladies ou de troubles oculaires. L'invention concerne en particulier l'amélioration de la dégénérescence maculaire, la rétinopathie diabétique et d'autres rétinopathies, ainsi que l'uvéite, la presbytie, la sécheresse oculaire, le glaucome, la blépharite et la rosacée de l'oeil. Les procédés comprennent l'administration d'une composition comprenant un support ou diluant acceptable d'un point de vue ophtalmique et un composé d'hydoxylamine en une quantité suffisante d'un point de vue thérapeutique pour prévenir ou retarder le développement ou réduire les symptômes d'un ou plusieurs états pathologiques ophtalmiques.

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