Amide and amino derivatives of a 2-substituted...

Details Amide and amino derivatives of a 2-substituted... Amide and amino derivatives of a 2-substituted...

C - Chemistry, Metallurgy

07

D

260/271.5

C07D 471/04 (2006.01) C07D 455/06 (2006.01)

Patent

CA 1118421

Docket No. 11855 AMIDE AND AMINO DERIVATIVES OF 2-SUBSTITUTED ANILINO-HEXAHYDROBENZO [a] QUINOLIZINES ABSTRACT OF THE DISCLOSURE Disclosed are novel 2-substituted anilino-hexahydrobenzo [a] quinolizines of the formula: Image wherein R and R' are independently H or -OCH3 and R" is Image , NH2, Image , Image , Image , Image , or Image . These compounds, and their pharma- cologically acceptable, non-toxic acid addition salts are useful as anti-hypertensive agents. Certain of the compounds disclosed herein elicit this effect without producing concomitant cardiac stimulation.

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