Amide and urea derivatives having anti-hypercholesteremic...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 311/82 (2006.01) A61K 31/16 (2006.01) A61K 31/195 (2006.01) A61K 31/335 (2006.01) A61K 31/415 (2006.01) A61K 31/665 (2006.01) C07C 233/24 (2006.01) C07C 233/25 (2006.01) C07C 233/26 (2006.01) C07C 235/48 (2006.01) C07C 235/56 (2006.01) C07C 275/32 (2006.01) C07D 311/90 (2006.01) C07D 313/12 (2006.01) C07D 313/14 (2006.01) C07D 405/12 (2006.01) C07D 521/00 (2006.01) C07F 9/655 (2006.01)

Patent

CA 2126994

Compounds of formula (I) are provided: (see formula I) wherein: R1 represents an alkyl group; or a group of formula (II), (III), (IV) or (V): (see formulas II, III, IV, V) and wherein the groups R2, R3, R4 and R5 are hydrogen or various organic groups; and pharmaceutically acceptable salts thereof; as well as methods for the preparation of such compounds and their use in the treatment and prophylaxis of hypercholesteremia and arteriosclerosis.

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