Amide compounds and thrombopoietin receptor activators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 231/18 (2006.01) A61K 31/381 (2006.01) A61K 31/4025 (2006.01) A61K 31/415 (2006.01) A61K 31/4155 (2006.01) A61K 31/4436 (2006.01) A61K 31/4535 (2006.01) A61K 31/5377 (2006.01) A61P 7/04 (2006.01) A61P 43/00 (2006.01) C07D 333/32 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2590204

A compound effective in the prevention, treatment, or alleviation of diseases in which thrombopoietin receptor activation is effective. It is a compound represented by the formula (1) (wherein A, B, R1, L1, R2, L2, L3, Y, L4, R3, and X are as defined in the description), a tautomer or prodrug of the compound, a pharmaceutically acceptable salt of either, or a solvate of these. (1)

La présente invention concerne un composé efficace dans la prévention, le traitement ou le soulagement de maladies dans lesquelles l~activation du récepteur de la thrombopoïétine est efficace. L~invention décrit un composé représenté par la formule (1) (dans laquelle A, B, R1, L1, R2, L2, L3, Y, L4, R3 et X sont tels que définis dans la description), un tautomère ou promédicament de ce composé, un sel pharmaceutiquement acceptable de l~un de ces deux éléments ou un solvate de ceux-ci. (1)

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