C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 413/06 (2006.01) A61K 31/5377 (2006.01) A61K 31/553 (2006.01) A61P 1/00 (2006.01) A61P 1/04 (2006.01) A61P 1/06 (2006.01) A61P 1/08 (2006.01) A61P 1/10 (2006.01) A61P 13/02 (2006.01) A61P 13/08 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2713412
Disclosed is a compound having a strong affinity to serotonin-4 receptors, which is useful as an enterokinesis-promoting agent or a digestive tract function-improving agent. Specifically, disclosed is a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof. Also specifically disclosed is a pharmaceutical composition containing a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof. [In Formula (1), Ar represents a group represented by Formula (Ar-1) or Formula (Ar-2).] (see formula 1) (see formula Ar-1) (see formula Ar-2)
L'invention porte sur un composé ayant une forte affinité pour les récepteurs de la sérotonine-4, qui est utile comme agent favorisant l'entérokinésie ou agent améliorant la fonction du tractus digestif. De façon spécifique, l'invention porte sur un composé représenté par la Formule (1) ou un sel pharmaceutiquement acceptable de celui-ci. Également de façon spécifique, l'invention porte sur une composition pharmaceutique contenant un composé représenté par la Formule (1) ou un sel pharmaceutiquement acceptable de celui-ci. [Dans la Formule (1), Ar représente un groupe représenté par la Formule (Ar-1) ou la Formule (Ar-2)].
Harada Hiroshi
Hirokawa Yoshimi
Kan Yoko
Kato Shiro
Nakamura Takanori
Dainippon Sumitomo Pharma Co. Ltd.
Kirby Eades Gale Baker
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