Amide derivative-containing pharmaceutical composition

Details Amide derivative-containing pharmaceutical composition Amide derivative-containing pharmaceutical composition

A - Human Necessities

61

K

A61K 31/4402 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/4192 (2006.01) A61K 31/421 (2006.01) A61K 31/4245 (2006.01) A61K 47/30 (2006.01) A61K 47/32 (2006.01) A61K 47/34 (2006.01) A61P 31/22 (2006.01)

Patent

CA 2728890

The present invention relates to a pharmaceutical composition containing a solid dispersion comprising an amide derivative or a salt thereof and a water-soluble polymer, wherein the pharmaceutical composition is not prepared by a melting method. The pharmaceutical composition contains the solid dispersion having an improved oral absorption, properties suitable for formulation, and an excellent stability.

Linvention concerne une composition pharmaceutique incluant une dispersion solide contenant un dérivé d'amide ou un sel de celui-ci et une substance polymère hydrosoluble. Ladite composition pharmaceutique nest pas préparée par procédé de fusion. Ladite composition pharmaceutique contient une dispersion solide permettant une absorption par voie orale améliorée et présente des caractéristiques adaptées à la préparation de médicaments, ainsi quune excellente stabilité.

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