Amide derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/04 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) C07D 211/22 (2006.01) C07D 211/70 (2006.01) C07D 403/04 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/06 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2141810

2141810 9403444 PCTABScor01 Amide derivatives of formula (1) and their pharmaceutically acceptable salts (where a and b each represent 0, 1, 2 or 3 such that a + b = 0, 1, 2 or 3, the dotted line represents an optional double bond, A is an optionally substituted C1-2-alkylene chain, R is mono or bicyclic aryl or heteroaryl radical, R1 is hydrogen or lower alkyl, R2 is an aryl, aralkyl, heteroaryl or heteroarylalkyl and -CONR3R4 represents a specified amide group) are 5-HT1A binding agents and may be used, for example, as anxiolytics.

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