Amide derivatives as gk activators

Details Amide derivatives as gk activators Amide derivatives as gk activators

C - Chemistry, Metallurgy

07

D

C07D 417/12 (2006.01) A61K 31/16 (2006.01) A61K 31/18 (2006.01) A61K 31/426 (2006.01) A61K 31/4402 (2006.01) A61K 31/505 (2006.01) A61K 45/06 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07D 213/75 (2006.01) C07D 239/42 (2006.01) C07D 277/46 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2471049

This invention relates to compounds of the general formula (I) which are activators of glucokinase (GK), and which may be useful for the management, treatment, control, or adjunct treatment of diseases or conditions, where increasing glucokinase activity is beneficial, for example diseases such as IGT, Syndrome X, type 2 diabetes, type 1 diabetes, dyslipidemia, hyperlipidemia, hypertension, and obesity.

La présente invention concerne des composés représentés par la formule (I) qui sont des activateurs de la glucokinase (GK) et qui peuvent être utiles pour la gestion thérapeutique, le traitement, la régulation ou le traitement d'appoint de maladies ou de troubles, dans lesquels une activité glucokinase accrue est bénéfique, par exemple les maladies telles que la diminution de la tolérance au glucose, le syndrome X, le diabète de type 2, le diabète de type 1, la dyslipidémie, l'hyperlipidémie, l'hypertension et l'obésité. Formule (I)

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