C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/28 (2006.01) A61K 31/505 (2006.01) A61P 3/00 (2006.01) C07D 213/80 (2006.01)
Patent
CA 2597148
This invention is concerned with compounds of the formula (I), wherein one of R5, R6 and R7 is formula (II) and R1 to R13, X1, X2, m and n are defined in the description, and all pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPAR.delta. and/or PPAR.alpha. agonists.
La présente invention concerne les composés de formule où l'un des groupements R5, R6 et R7 représente et R1 à R13, X1, X2, m et n sont définis dans la description, ainsi que tous les sels et/ou esters de qualité pharmaceutique desdits composés. L'invention concerne en outre des préparations pharmaceutiques contenant de tels composés, un procédé de synthèse de tels composés et leur emploi dans le traitement prophylactique et/ou thérapeutique de maladies modulées par les agonistes de PPAR.delta. et/ou PPAR.alpha..
Ackermann Jean
Aebi Johannes
Binggeli Alfred
Grether Uwe
Kuhn Bernd
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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