Amide derivatives of p-isobutyl-phenyl-propionic acid,...

Details Amide derivatives of p-isobutyl-phenyl-propionic acid,... Amide derivatives of p-isobutyl-phenyl-propionic acid,...

C - Chemistry, Metallurgy

07

C

260/552.7, 260/5

C07C 233/12 (2006.01)

Patent

CA 1181419

ABSTRACT The amide derivatives of p-isobutyl-phenyl-propionic acid, having general formula Image wherein X is the radical of a substituted amine, of the group comprising lysino, metatrifluorotoluidine, glutamic arid and aspartic acid, snow a good anti-inflammatory activity, accompanied by favourable side properties. For the preparation of the compounds of the invention, the p-isobutyl- phenyl-propionic acid is chlorinated, and the chlorinated derivative is reacted with the proper substituted amine.

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