Amide derivatives of vlb, leurosidine, leurocristine and...

Details Amide derivatives of vlb, leurosidine, leurocristine and... Amide derivatives of vlb, leurosidine, leurocristine and...

C - Chemistry, Metallurgy

07

D

260/237.3

C07D 519/04 (2006.01)

Patent

CA 1067073

Abstract The invention relates to a process for preparing novel dimeric alkaloid derivatives of vinblastine, vin- cadioline and leurocolombine by reacting vinblastine, vincadioline or leurocolombine with an amine and, if desired, reacting the resulting compound with a nitrosating agent and an amine.

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