Amide-substituted 1,2,4-triazin-5(2h)-ones for the treatment...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) A61K 31/53 (2006.01) A61P 29/00 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2530816

The invention relates to amide-substituted 1,2,4-triazin-5(2H)-ones, to methods for the production thereof, and to the use of the same for producing medicaments for the treatment and/or prophylaxis of diseases, especially chronically inflammatory diseases such as rheumatoid diseases, and cardiovascular diseases such as dyslipidemia, arteriosclerosis and coronary heart diseases Formula (I).

L'invention concerne des 1,2,4-triazino-5(2H)-ones à substitution amide et des procédés de fabrication de ces composés, ainsi que leur utilisation dans la fabrication de médicaments destinés au traitement et/ou à la prophylaxie de maladies, notamment de maladies inflammatoires chroniques telles que par ex. des maladies rhumatoïdes, et de maladies cardiovasculaires telles que par ex. des dyslipidémies, l'artériosclérose et des maladies cardiaques coronariennes Formule (I).

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