C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/02 (2006.01) C07D 471/06 (2006.01)
Patent
CA 2559863
Imidazopyridine, imidazoquinoline, and imidazonaphthyridine compounds having an amide substituent at the 1-position, pharmaceutical compositions containing the compounds, intermediates, and methods of making and methods of use of these compounds as immunomodulators, for modulating cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
La présente invention concerne des composés d'imidazopyridines, d'imidazoquinoline et d'imidazonaphthyridine à substitution amide en position 1. L'invention concerne également des compositions pharmaceutiques à base de ces composés, ainsi que des intermédiaires et des procédés de fabrication des ces composés. L'invention concerne enfin des procédés permettant l'utilisation de ces composés aux fins de modulation immunitaire, notamment dans le cas de la biosynthèse cytokinique chez des animaux, et dans le cas d'un traitement d'affections, en particulier d'infections virales et néoplasiques.
Amos David T.
Dellaria Joseph F. Jr.
Duffy Daniel E.
Krepski Larry R.
Moser William H.
3m Innovative Properties Company
Robic
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