C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 473/04 (2006.01) A61K 31/522 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2487033
The present invention is a 1,3,8 substituted xanthine derivative of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2 and R3 are as defined in the specification. Compounds of formula (I) and pharmaceutically acceptable salts or prodrugs thereof show activity as modulators of gluconeogenesis.
L'invention concerne un dérivé de 1,3,8 xanthine substitué de formule I, ou d'un sel de ce dernier pharmaceutiquement acceptable. R?1¿, R?2¿ et R?3¿ sont tels que définis dans le descriptif. Des composés de la formule I et des sels pharmaceutiquement acceptables ou des promédicaments de ceux-ci présentent une activité comme modulateurs de la gluconéogénèse.
Dunten Pete William
Foley Louise Helen
Huby Nicholas John Silvester
Pietranico-Cole Sherrie Lynn
Yun Weiya
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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