Amide tetrazole acat inhibitors

Details Amide tetrazole acat inhibitors Amide tetrazole acat inhibitors

C - Chemistry, Metallurgy

07

D

C07D 257/04 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 231/12 (2006.01) C07D 233/54 (2006.01) C07D 249/04 (2006.01) C07D 261/08 (2006.01) C07D 271/06 (2006.01) C07D 271/10 (2006.01) C07D 277/22 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2114017

Pharmaceutically useful compounds having ACAT inhibitory activity of formula (1) wherein n is zero, one or two; R1 is phenyl; substituted phenyl, naphthyl, substituted naphthyl, a heteroaromatic group or a hydrocarbon group having from 1 to 18 carbon atoms; R2 and R3 are hydrogen, halo, hydroxy, alkyl, alkenyl, cycloalkyl, phenyl, substituted phenyl, a heteroaryl, or form a spiroalkyl group, and R4 is a hydrocarbon group having from 1 to 20 carbon atoms.

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