C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/20 (2006.01) A61K 31/27 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) C07C 237/22 (2006.01) C07C 271/22 (2006.01) C07D 209/54 (2006.01) C07D 217/06 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 491/10 (2006.01) C07D 491/113 (2006.01) C07D 495/10 (2006.01) C07D 497/10 (2006.01)
Patent
CA 2097069
2097069 9210479 PCTABS00013 Bicyclic and polycyclic amidic derivatives of glumatic, aspartic and 2-amino adipic acids having activities antagonistic to gastrin, of general formula (I) in which r is between 1 and 3 and R1 is selected from mono- and disubstituted phenyl groups, and in which the substituents are selected from chlorine, linear and branched C1-C4 alkyl groups, cyano, nitro, methoxy, and trifluoromethyl groups, and the 2(beta)-naphthyl group, and heterocyclic, monocyclic or bicyclic groups containing one heteroatom such as nitrogen, oxygen or sulphur and selected from furyl, thiophenyl, pirrolyl, pyridinyl, and pyridinyl-N-oxide unsubstituted or mono- or disubstituted with methyl and chlorine, indolyl, thionaphthyl, benzofuranyl, quinolinyl, or isoquinolinyl groups, and in which R2 is selected independently from a heterocyclic spiro group, a bicyclic spiro amino group, a bicyclic amino group (condensed) and an adamantyl alkyl amino group.
Makovec Francesco
Rovati Claudio Lucio
Rovati Luigi Angelo
Macrae & Co.
Rotta Research Laboratorium S.p.a.
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