C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/472, 260/468
C07D 317/68 (2006.01) C07C 279/18 (2006.01)
Patent
CA 1177488
ABSTRACT OF THE DISCLOSURE Amidino compounds represented by the formula Image and pharmaceutically acceptable acid addition salts thereof are novel compounds and are useful as powerful anti- trypsine, antiplasmin, antikallikrein and antithrombin agents. Having strong anti-C1 (C1?, C1?) activities and an anticomplement activity, they are also useful as anti- complement agents. These amidino compounds are prepared by usual esterification of carboxylic acid compounds represented by the formula Image with 6-amidino-2-naphthol and, if necessary, can be transformed into pharmaceutically acceptable acid addi- tion salts thereof.
385570
Fujii Setsuro
Kumuri Masateru
Nakayama Toyoo
Toshiyuki Okutome
Yaegashi Takashi
Fetherstonhaugh & Co.
Torii & Co. Ltd.
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