Amidine derivatives of mitomycin a, mitomycin c and...

Details Amidine derivatives of mitomycin a, mitomycin c and... Amidine derivatives of mitomycin a, mitomycin c and...

C - Chemistry, Metallurgy

07

D

260/255, 260/279

C07D 487/04 (2006.01) C07D 487/14 (2006.01)

Patent

CA 1230333

Abstract of the Disclosure Mitcmycin A, mitomycin C, and porfiromycin react with amide acetals and other amide derivatives to produce amidine derivatives having antitumor activity against experimental animal tumors. The amidines derived from mitcmycin C are useful intermediates in reactions with primary amines to produce both known and novel 7-amino-9a-methoxymitosanes having antitumor activity against experimental animal tumors.

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