Amidine derivatives, their preparation and application as...

C - Chemistry – Metallurgy – 07 – D

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C07D 333/36 (2006.01) A61K 31/38 (2006.01) A61K 31/495 (2006.01) C07D 209/08 (2006.01) C07D 333/38 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01) C07D 473/08 (2006.01)

Patent

CA 2344224

The invention concerns novel amidine derivatives, and in particular the following compounds: 2-hydroxy -5-methoxy -N-{2-[4-[(2 -thienyl(imino) methyl) amino]phenyl]ethyl} -benzamide; 2.5-dihydroxy -N-{2-[4[2 -thienyl(imino)methyl) amino]phenyl]ethyl} -benzamide ; and their use as medicines and pharmaceutical compositions containing them.

La présente invention concerne de nouveaux dérivés d'amidines, et en particulier les composés suivants: 2-hydroxy -5-méthoxy -N-{2-[4-[(2 - thiényl(imino) méthyl) amino]phényl]éthyl} -benzamide; 2,5-dihydroxy -N-{2- [4[(2 -thiényl(imino) méthyl) amino]phényl]éthyl} -benzamide; ainsi que leur utilisation comme médicaments et les compositions pharmaceutiques les contenant.

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