C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/20 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) C07D 209/14 (2006.01) C07D 401/12 (2006.01)
Patent
CA 2100034
ABSTRACT Amidines derived from 3-aminoethyl indoles and process for the preparation thereof. Amidines derived from 3-aminoethyl indoles of formula (I) Image (I) where: R1 is an atom of hydrogen or a lower alkyl or alkenyl group: R2 is an atom of hydrogen or a lower alkyl or alkenyl, aryl, arylalkyl or cycloalkyl group; R3 and R4 may be the same or different and are an atom of hydrogen or a lower straight or branched chain alkyl group; and R5 is an atom of hydrogen; a straight or branched chain alkyl, alkenyl or alkynyl group, which may be substituted with an hydroxy group, alkoxy, alkoxycarbonyl, carboxyl, trifluoromethyl, halogen, carbonyl, cyano; a cyano group, phenyl, aryl, cycloalkyl, heterocycle or arylalkyl, optionally substituted with a hydroxy, alkoxy, halogen, amino, alkoxycarbonyl, carboxyl, trifluoromethyl, carbonyl, cyano, nitro, lower alkyl, lower alkenyl, or may form an optionally substituted heterocycle with R4 and with the nitrogen atom; and the physiologically acceptable salts thereof.
Acin Joan M. R.
Barjoan Pere D.
Ges Jose M. C.
Olondriz Francisco M.
Rovira Anna B.
Bereskin & Parr
Vita-Invest S.a.
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