Amidino compounds as cysteine protease inhibitors

Details Amidino compounds as cysteine protease inhibitors Amidino compounds as cysteine protease inhibitors

C - Chemistry, Metallurgy

07

C

C07C 311/18 (2006.01) A61K 31/18 (2006.01) A61K 31/38 (2006.01) A61K 31/41 (2006.01) A61P 9/10 (2006.01) A61P 17/06 (2006.01) A61P 25/28 (2006.01) A61P 29/02 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) C07C 311/54 (2006.01) C07D 263/56 (2006.01) C07D 335/02 (2006.01)

Patent

CA 2526694

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

La présente invention concerne en particulier des composés qui sont des inhibiteurs de protéases à cystéine, en particulier de cathepsines B, K, L, F et S, et qui servent par conséquent au traitement de maladies induites par ces protéases. Cette invention concerne également des compositions pharmaceutiques comprenant ces composés ainsi que des procédés de préparation de ces compositions.

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