Amidino compounds useful as nitric oxide synthase inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 323/58 (2006.01) A61K 31/155 (2006.01) A61P 29/00 (2006.01) C07C 317/48 (2006.01) C07C 323/59 (2006.01) C07D 233/76 (2006.01) C07D 271/06 (2006.01) C07D 271/07 (2006.01) C07D 277/56 (2006.01)

Patent

CA 2402199

The present invention relates to amidino compounds of formula (I), in which the variables are as defined in the claims, and salts thereof. In another embodiment the present invention also provides a use of the present compounds as nitric oxide synthase inhibitors. In a further embodiment, the present invention provides methods for making the amidino compounds and other compounds (I).

La présente invention concerne des composés amidino représentés par la formule (I) et certains de leurs sels, formule dans laquelle les variables sont telles que définies dans les revendications. Selon un autre mode de réalisation, la présente invention concerne également l'utilisation des présents composés, notamment comme inhibiteurs de la synthase du monoxyde d'azote. Selon encore un autre mode de réalisation, la présente invention concerne des procédés d'élaboration de ces composés amidino et d'autres composés.

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