Amidinohydrazones of ketones derived from benzo[b]furan,...

C - Chemistry – Metallurgy – 07 – D

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C07D 307/81 (2006.01) A61K 31/34 (2006.01) A61K 31/395 (2006.01) C07D 405/00 (2006.01)

Patent

CA 2192044

New amidinohydrazones of ketones are provided herein which are derived from benzo[b]furan having the general Formula I (see fig. I) I and their pharmaceutically acceptable salts. A process for their production, as well as pharmaceuticals containing these compounds are also provided. The compounds described show improved effects of class III antiarrhythmic agents.

ouvelles amidinohydrazones de cétones dérivées du benzo¢b!furane de formule générale I (voir la fig. I) (I) et leurs sels acceptables sur le plan pharmaceutique. La revendication comprend également un procédé de fabrication des composés susmentionnés ainsi que les produits pharmaceutiques renfermant ces composés. Les composés décrits améliorent les effets des antiarythmisants de classe III.

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