Amidinourea process and pharmaceutical composition

C - Chemistry – Metallurgy – 07 – D

Patent

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260/543.7, 260/3

C07D 295/20 (2006.01) C07C 129/12 (1985.01) C07C 147/12 (1985.01)

Patent

CA 1230886

Abstract An improved process for the preparation of an amidinourea of the formula Image wherein the improvement comprises the use of a ketone as the reaction medium and the resulting amidinourea is obtained in higher yield and greater purity. The amidinoureas prepared according to the present invention are known anti-diarrheal agents.

474424

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