Amidinoureas

Details Amidinoureas Amidinoureas

C - Chemistry, Metallurgy

07

D

260/244.1, 260/5

C07D 265/02 (2006.01) C07C 129/12 (1980.01)

Patent

CA 1086731

ABSTRACT OF THE DISCLOSURE The invention relates to a compound of the formula: Image where R2, R3, R4, R5 and R6 may be the same or different and are hydrogen. halo, loweralkyl, haloloweralkyl, nitro, amino, acylamino, hydroxy, aralkyloxy or loweralkoxy; Rn is hydrogen or loweralkyl; R7, R8, R9 and R10 may be the same or different and are hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl or aralkyl; R7 and R8 together and R9 and R10 together may form a 5-7 atom ring which may further include 0-1 hetero atoms of N, O or S; x is 0-1; the sum total of carbon atoms present in R7, R8, R9 and R10 together is less than twelve; and the non-toxic acid addition salts thereof. These compounds have valuable properties as anti- secretory, anti-spasmodic, anti-ulcerogenic and anti-diarrheal agents.

275140

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