Amido ether substituted imidazoquinolines

Details Amido ether substituted imidazoquinolines Amido ether substituted imidazoquinolines

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01)

Patent

CA 2436980

Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and amide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

L'invention concerne des composés à base d'imidazoquinoline et de tétrahydroimidazoquinoline, comportant une fonctionnalité éther et amide en position 1, qui sont utiles comme modificateurs de réponse immune. Les composés et les compositions décrits dans l'invention peuvent induire la biosynthèse de diverses cytokines et sont utiles dans le traitement d'une série d'états pathologiques, y compris les maladies virales et néoplasiques.

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