Amidoalkyl-piperidine and amidoalkyl-piperazine derivatives...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/10 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61P 25/00 (2006.01) C07D 211/16 (2006.01) C07D 213/44 (2006.01) C07D 213/75 (2006.01) C07D 295/192 (2006.01) C07D 307/46 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/06 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2427296

Novel amidoalkyl-piperidine and amidoalkyl-piperazine derivatives of the general formula wherein all variables are as described herein, useful in the treatment of disorders, such as depression, dementia, schizophrenia, bipolar disorders, anxiety, emesis, acute or neuropathic pain, itching, migraine and movement disorders.

La présente invention concerne de nouveaux dérivés d'amidoalkyl-piperidine et d'amidoalkyl-piperazine de la formule générale, dont toutes les variables sont telles que décrites ci-dessus. Ces dérivés sont utilisés dans le traitement de troubles, tels que la dépression, la démence, la schizophrénie, les troubles bipolaires, l'anxiété, le vomissement, les douleurs neuropathiques ou aiguës, les démangeaisons, la migraine et les troubles de la motilité.

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