Amidobenzamides, their salts, process for their preparation...

C - Chemistry – Metallurgy – 07 – D

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260/363, 260/328

C07D 307/54 (2006.01) C07D 307/52 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 1190927

ABSTRACT OF THE DISCLOSURE Amidobenzamides having histamine H2 receptors antagonising ac- tion, of formula Image wherein A is CO or SO2 and B is alkyl, phenyl, pyridyl, pyri- dyl 1-oxyde, pyrazinyl or thienyl; their salts; a process for their preparation comprising reacting the 2-(5-dimethylamino- methylfuran-2-ylmethylthio)ethylamine with a functional deri- vative of a benzoic acid of formula Image and optionally transforming the product obtained into their salts; and pharmaceutical compositions useful for the treat- ment of the ulcerous disease.

406813

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