Amidobenzenes

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 317/50 (2006.01) A61K 31/165 (2006.01) C07C 313/04 (2006.01) C07C 317/40 (2006.01) C07C 323/41 (2006.01) C07C 323/60 (2006.01) C07C 323/65 (2006.01)

Patent

CA 2048318

ABSTRACT AMIDOBENZENES The invention concerns novel phenoxy- and phenylthio-acetyl derivatives of (4-amino-2,6-dimethylphenylsulphonyl)nitromethane and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, in the treatment of certain peripheral effects of diabetes and galactosemia. Also disclosed are pharmaceutical compositions containing one of the derivatives and processes for the manufacture and use of the derivatives.

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