Amination of carbonyls

Details Amination of carbonyls Amination of carbonyls

C - Chemistry, Metallurgy

07

C

260/605.4

C07C 209/48 (2006.01) C07C 209/26 (2006.01) C07C 211/36 (2006.01)

Patent

CA 2015251

- 52 - AMINATION OF CARBONYLS Abstract of the Disclosure Organic compounds containing at least one carbonyl group are reductively aminated to minimize the formation of hydroxylated side product by the use of at least one of (i) an amination promoter, (ii) water removal, (iii) lower hydrogen partial pressure during the formation of an imine or enamine intermediate or (iv) primary or secondary amine reactant to form an imine or enamine intermediate.

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