Amine and amide derivatives as ligands for the neuropeptide...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) A61K 31/444 (2006.01) A61K 31/4523 (2006.01) A61P 25/00 (2006.01) C07C 311/18 (2006.01) C07C 311/19 (2006.01) C07D 211/34 (2006.01) C07D 213/38 (2006.01) C07D 213/40 (2006.01) C07D 295/14 (2006.01) C07D 295/15 (2006.01) C07D 333/20 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 409/14 (2006.01) C07D 471/10 (2006.01)

Patent

CA 2380032

Amine and amide derivatives of formula (A) which are ligands for the neuropeptide Y Y5 (NPY5) receptor, methods of preparation and pharmaceutical compositions containing amines and amides of formula (A) as the active ingredient are described. The amines and amides of formula (A) are useful in the treatment of disorders and diseases associated with NPY receptor subtype Y5.

L'invention concerne des dérivés d'amines et d'amides de formule (A), qui constituent des ligands pour le récepteur Y5 du neuropeptide Y (NPY5), des procédés de préparation et des compositions pharmaceutiques contenant des amines et des amides de formule (A) en tant qu'ingrédient. Les amines et amides de formule A sont utiles dans le traitement de troubles et de maladies associés au sous-type Y5 de récepteur de NPY.

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