Amine salts of a crth2 antagonist

Details Amine salts of a crth2 antagonist Amine salts of a crth2 antagonist

C - Chemistry, Metallurgy

07

D

C07D 239/48 (2006.01) A61K 31/33 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2690436

Provided are amine salts of {4,6-bis(dimethylamino)-2-(4-(4- (trifluoromethyl)benzamido)benzyl)pyrimidin-5-yl}-acetic acid, processes for their preparation, pharmaceutical compositions containing them, and their use for treating, preventing, or ameliorating one or more symptoms of a CRTH2-mediated disorder or disease.

L'invention porte sur des sels d'amines d'acide {4,6-bis(diméthylamino)-2-(4-(4-(trifluorométhyl)benzamido)benzyl)pyrimidin-5-yl}-acétique, sur des procédés permettant de les préparer, sur des compositions pharmaceutiques les contenant et sur leur utilisation pour le traitement, la prévention ou l'amélioration d'un ou plusieurs symptôme d'un trouble ou d'une maladie à médiation par CRTH2.

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