Amines

Details Amines Amines

C - Chemistry, Metallurgy

07

D

260/514, 260/476

C07D 295/185 (2006.01) C07C 59/88 (2006.01) C07D 263/34 (2006.01)

Patent

CA 1068695

ABSTRACT OF THE DISCLOSURE The invention concerns .alpha.-aminoacyl derivatives of phenyl-, phenoxy-, thiophenoxy- and phenylsulphinyl- alkanoic acids together with their amides, esters and pharmaceutically acceptable salts; processes for their preparation; and pharmaceutical compositions for therapeutic use in inhibiting the formation of thrombi and also in reducing the persistence of thrombi formed in the blood of warm blooded animals. Representative compounds of the invent on are methyl 4-(aminoacetyl)phenoxyacetate, 4-(aminoacetyl)phenoxyacetic acid and methyl 4-(aminoacetyl)- thiophenoxyacetate, preferably as their hydrochlorides.

265534

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