Amines and amides for the treatment of diseases

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/165 (2006.01) A61K 31/40 (2006.01) A61K 31/437 (2006.01) A61P 1/00 (2006.01) A61P 1/16 (2006.01) A61P 3/00 (2006.01) A61P 11/00 (2006.01) A61P 19/02 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2556914

Compositions and methods are disclosed for inhibiting semicarbazide-sensitive amine oxidase (SSAO), also known as vascular adhesion protein-1 (VAP-1). The compounds disclosed are amine-containing and amide-containing compounds. The compounds and compositions are useful for treatment of diseases, including inflammation, inflammatory diseases and autoimmune disorders.

L'invention concerne des compositions et des méthodes destinées à inhiber l'amine oxidase sensible aux semicarbazides (SSAO), également connue sous le nom de protéine d'adhésion vasculaire 1 (VAP-1). Les composés de l'invention contiennent de l'amine et de l'amide. Ces composés et compositions sont utiles pour le traitement de maladies, telles que l'inflammation, les maladies inflammatoires et les maladies auto-immunes.

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