Amino acid derivative

Details Amino acid derivative Amino acid derivative

C - Chemistry, Metallurgy

07

C

C07C 327/30 (2006.01) A61K 31/21 (2006.01) A61K 31/33 (2006.01) C07C 237/02 (2006.01) C07C 237/08 (2006.01) C07C 237/20 (2006.01) C07C 237/22 (2006.01) C07C 271/22 (2006.01) C07C 323/41 (2006.01) C07C 323/60 (2006.01) C07C 327/34 (2006.01) C07C 329/06 (2006.01) C07D 209/18 (2006.01) C07D 209/20 (2006.01) C07D 213/78 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 213/83 (2006.01) C07D 233/54 (2006.01) C07D 233/64 (2006.01) C07D 277/30 (2006.01) C07D 307/68 (2006.01) C07D 317/38 (2006.01) C07D 317

Patent

CA 2112690

Constitution: an amino acid derivative represented by the general formula (I): R1NH-CH(R2)-CONH-A-ONO2 and a pharmacologically acceptable salt thereof, wherein R1 represents hydrogen, C1-C7 alkanoyl, C1-C6 alkoxycarbonyl, C6-C10 arylcarbonyl, C7-C13 aralkylcarbonyl, C7-C13 aralkyloxycarbonyl, or 5- or 6-membered heteroarylcarbonyl: R2 represents substituted C1-C6 alkyl; and A represents C2-C5 alkylene. Effects this compound is excellent in a collateral vessel dilator activity and an antianginal activity, and hence useful as an antianginal drug.

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