C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 263/06 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2044564
RAN 4019/111 Abstract The compounds of the formula Image I wherein A, B, X, Y, R1, R2, R3. R4 and R5 have the significance given in claim 1, in the form of optically pure diastereomers, mixtures of diastereomers, diastereomeric racemates or mixtures of diastereomeric racemates as well as pharmaceutically usable salts thereof inhibit the activity of the natural enzyme renin and can accordingly be used in the form of pharmaceutical preparations in the control or prevention of high blood pressure and cardiac insufficiency. They can be manufactured according to various methods which are known per se.
Branca Quirico
Heitz Marie-Paule
Muller Marcel
Neidhart Werner
Stadler Heinz
Branca Quirico
Gowling Lafleur Henderson Llp
Heitz Marie-Paule
Hoffmann-La Roche (f.) Co. Aktiengesellschaft
Muller Marcel
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