Amino acid derivatives

Details Amino acid derivatives Amino acid derivatives

C - Chemistry, Metallurgy

07

D

C07D 213/56 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) C07C 317/44 (2006.01) C07C 323/56 (2006.01) C07D 233/54 (2006.01) C07D 233/64 (2006.01)

Patent

CA 2095671

RAN 4019/120 Abstract The compounds of the formula Image l wherein R1 signifies imidazolylmethyl or pyridylmethyl and A signifies carboxyl, benzyloxycarbonyl, hydroxymethyl or alkylcarbonyloxymethyl, in the form of optically pure diastereomers, mixtures of dia- stereomers, diastereomeric racemates or mixtures of diastereo- meric racemates as well as pharmaceutically usable salts thereof inhibit the activity of the natural enzyme renin and can accordingly be used in the form of pharmaceutical preparations in the control or prevention of high blood pressure and cardiac insufficiency. They can be manufactured according to various methods which are known per se.

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