Amino acid derivatives

Details Amino acid derivatives Amino acid derivatives

C - Chemistry, Metallurgy

07

K

C07K 5/00 (2006.01) A61K 38/04 (2006.01) C07D 211/58 (2006.01) C07D 233/54 (2006.01) C07D 401/12 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2046112

A b s t r a c t Novel amino acid derivative of the formula I X-W-CR1R2-CO-Y-NH-CHR4-CR5-CR2-(CR6R7)rS(O)t-CH2-CO-V-R3 I in which X, W, R1, R2, Y, R4, R5, R6, R7, r, t, V and R3 have the meanings indicated in patent Claim 1, inhibit the activity of human plasma renin and can be used for the treatment of cardiac, circulatory and vascular diseases.

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