Amino acid derivatives

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 235/26 (2006.01) A61K 31/395 (2006.01) C07C 233/19 (2006.01) C07C 317/44 (2006.01) C07C 317/50 (2006.01) C07C 323/60 (2006.01) C07D 207/08 (2006.01) C07D 207/12 (2006.01) C07D 211/22 (2006.01) C07D 213/40 (2006.01) C07D 213/53 (2006.01) C07D 213/56 (2006.01) C07D 233/54 (2006.01) C07D 233/61 (2006.01) C07D 277/30 (2006.01) C07D 295/088 (2006.01) C07D 295/185 (2006.01) C07D 295/205 (2006.01) C07D 307/54 (2006.01) C07D 317/24 (2006.01) C07D 333/24 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07

Patent

CA 2064955

RAN 4019/116 Abstract The compounds of the formula I Image wherein A, R1, R2, R3, R4 and R5 have the significance given in claim 1, in the form of optically pure diastereomers, mixtures of diastereomers, diastereomeric racemates or mixtures of diastereomeric racemates as well as pharmaceutically usable salts thereof inhibit the activity of the natural enzyme renin and can accordingly be used in the form of pharamaceutical preparations in the control or prevention of high blood pressure and cardiac insufficiency. They can be manufactured according to various methods which are known per se.

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