C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/12 (2006.01) A61K 31/454 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2336162
Compounds represented by general formula (I) and salts thereof, wherein each symbol is as defined in the specification. Because of inhibiting the N type calcium channel, the compounds of general formula (I) are useful as preventives and/or remedies for brain infarction, transient ischemic attack, cerebrospinal failure following heart operation, spinal vascular failure, stress hypertension, neurosis, epilepsy, asthma, frequent urination, etc. or analgesics.
L'invention concerne des composés de la formule générale (I) et des sels desdits composés. Dans ladite formule, chaque symbole est tel que défini dans le mémorandum descriptif. Les composés de l'invention inhibent les canaux calciques de type N et sont donc efficaces comme agents de prévention et/ou de traitement de l'infarctus cérébral, de l'accident ischlmique transitoire, des troubles cérébro-spinaux consécutifs à une opération cardiaque, des lésions vasculaires de la moelle épinière, de l'hypertension liée au stress, de la névrose, de l'épilepsie, de l'asthme, des mictions fréquentes, etc., ou comme analgésiques.
Kato Masashi
Seko Takuya
Ono Pharmaceutical Co. Ltd.
Riches Mckenzie & Herbert Llp
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