A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/166 (2006.01) A61K 31/277 (2006.01) A61K 31/44 (2006.01)
Patent
CA 2688267
Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity are disclosed. Specifically, a series of compounds containing both an amino acid functionality and multiple aromatic rings are disclosed of the general formula (1) where X is benzhydryl, or an aromatic or heteroaromatic ring.
L'invention concerne des procédés et des composés efficaces pour améliorer des conditions caractérisées par une activité des canaux calciques non souhaitée, en particulier une activité des canaux calciques de type N et/ou de type T non souhaitée. Spécifiquement, l'invention concerne une série de composés contenant à la fois une fonctionnalité d'acide aminé et de multiples cycles aromatiques de la formule générale (I) dans laquelle X est benzhydryle, ou un cycle aromatique ou hétéro-aromatique.
Chahal Navjot
Ding Yanbing
Duffy Joseph
Galemmo Robert Jr.
Holland Richard
Fetherstonhaugh & Co.
Neuromed Pharmaceuticals Ltd.
Zalicus Pharmaceuticals Ltd.
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