C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 323/60 (2006.01) A61K 31/16 (2006.01) A61K 31/381 (2006.01) A61K 31/395 (2006.01) A61K 31/405 (2006.01) A61P 9/10 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01) C07D 209/18 (2006.01) C07D 213/75 (2006.01) C07D 263/58 (2006.01) C07D 277/28 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2621445
The present invention relates to compounds of formula (I): or pharmaceutically acceptable salts or stereoisomers thereof. The compounds of the present invention are inhibitors of histone deacetylase (HDAC) and are useful for treating cellular proliferative diseases, including cancer. Further, the compounds of the present invention are useful for treating neurodegenerative diseases, schizophrenia and stroke among other diseases.
L'invention concerne des composés de la formule (I), ou des sels pharmaceutiquement acceptables ou des stéréoisomères de ceux-ci. Ces composés, qui sont des inhibiteurs de l'histone déacétylase (HDAC), sont utilisés dans le traitement de maladies à prolifération cellulaire, y compris le cancer. De plus, ces composés sont utilisés dans le traitement de maladies neurodégénératives, de la schizophrénie et de l'accident vasculaire cérébral, notamment.
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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