Amino acid derivatives of daryl 1,3,4-oxadiazolone

C - Chemistry – Metallurgy – 07 – D

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C07D 271/113 (2006.01) A61K 31/41 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2319629

The present invention provides novel amino acid derivatives having general formula (I), wherein R1, R2 and R3 are as defined herein, or a nontoxic phamaceutically acceptable salt or solvate thereof and are useful in the treatment of disorders which are responsive to the opening of potassium channels.

La présente invention concerne de nouveaux dérivés aminoacides de formule générale (I), dans laquelle R?1¿, R?2¿, R?3¿ sont tels que définis dans l'invention. Cette invention concerne également un sel ou un produit de solvatation pharmaceutiquement acceptable de ces dérivés, qui peuvent être utilisé pour traiter les troubles liés à l'ouverture de canaux potassium.

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