Amino acid derivatives of indolinone based protein kinase...

Details Amino acid derivatives of indolinone based protein kinase... Amino acid derivatives of indolinone based protein kinase...

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01) A61K 31/404 (2006.01)

Patent

CA 2635360

Amino acid derivatives of pyrrolyl-indolinones and their amide or ester derivatives have enhanced and unexpected drug properties as inhibitors of protein kinases and are useful in treating disorders related to abnormal protein kinase activities such as cancer.

L'invention concerne des dérivés d'acides aminés de pyrrolyl-indolinones et leurs dérivés amide ou ester, qui possèdent de façon inattendue des propriétés thérapeutiques accrues et sont utiles comme inhibiteurs de protéines kinases et pour traiter des troubles liés à des activités anormales de protéines kinases telles que le cancer.

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