Amino acid-derived diaminopropanols

Details Amino acid-derived diaminopropanols Amino acid-derived diaminopropanols

C - Chemistry, Metallurgy

07

C

C07C 271/10 (2006.01) C07C 213/00 (2006.01) C07C 213/02 (2006.01) C07C 215/18 (2006.01) C07C 215/28 (2006.01) C07C 215/30 (2006.01) C07C 233/36 (2006.01) C07C 255/24 (2006.01) C07C 269/06 (2006.01) C07C 271/16 (2006.01) C07C 273/18 (2006.01) C07C 275/24 (2006.01) C07C 311/18 (2006.01) C07C 323/43 (2006.01) C07D 207/08 (2006.01) C07D 207/09 (2006.01) C07D 207/12 (2006.01) C07D 209/20 (2006.01) C07D 233/64 (2006.01) C07C 271/20 (2006.01) C07C 275/14 (2006.01)

Patent

CA 2194480

The present invention relates to a method of forming a 1,3-diamino-3- substituted-2-propanol chemical intermediate from which various chemicals, such as selected protease-inhibitors and other drugs, as well as polymers, can be synthesized. The method includes contacting a nitromethyl amino acid compound with at least one reducing agent to form the 1,3-diamino-3- substituted-2-propanol chemical intermediate.

La présente invention se rapporte à un procédé de fabrication d'un produit chimique intermédiaire 1,3-diamino-2-propanol substitué en position 3 à partir duquel on peut réaliser la synthèse de divers produits chimiques, tels que des inhibiteurs sélectionnés de la protéase et autres médicaments, ainsi que de polymères. Le procédé consiste à mettre en contact un composé d'amino-acide nitrométhylé avec au moins un agent de réduction afin d'obtenir le produit chimique intermédiaire 1,3-diamino-2-propanol substitué en position 3.

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